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Utility of the MaxCyte at the Scripps Research Institute Molecular Screening Center

Timothy Spicer
Monday, April 13, 2015
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Chapters

  • Introduction
  • Overview of Presentation
  • Scripps Florida
  • Screening Process
  • SRIMSC: Targets, Type and Class 2005-2015
  • SRIMSC: Probe Development and Project Classification 2005-2015
  • Compound Management Properties of the Scripps Drug Discovery Library SDDL
  • SRIMSC: Sample Storage and Reformatting
  • Plate-based Assay Development & Miniaturization Labs
  • Cell Culture and Reagent Development Labs
  • Automated High-Throughput Screening Robotic Arm
  • Our HTS Readers
  • Justification for the MaxCyte
  • Phenotypic Analysis and HCS
  • The MaxCyte STX Scalable Transfection System at a Glance
  • Protocol
  • Principle
  • MaxCyte Data Result examples
  • MaxCyte STX-Acceptance Tests
  • Chemical vs. MaxCyte Transfection
  • Titration Experiment using MaxCyte
  • Typical HTS FLIPR Assay Protocol
  • Summary
  • SRIMSC: 3 Compounds in the Clinic!!
  • Thank You!
 

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