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DEPArray™ technology: bringing precision to precision medicine

Nicolò Manaresi, PhD
Monday, November 28, 2016
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Chapters

  • Introduction
  • DEPArray™ digital sorting
  • Scientific Reports
  • DEPArray™ NxT: boost the power of Next Generation Sequencing
  • Mainstreming DEPArray™ on FFPE: Enabling analysis of small biopsies & low tumor content
  • DEPArray™ OncoSeek panel
  • DEPArray™ sorting offsets true-variants dilution by normal cells
  • Purity bring clarity in CNA assessment
  • DEPArry™ LibPrep: enabling low-input large-scale analysis
  • Enable extracting digital copy-number analysis
  • Divide and conquer
  • Identification of clinically relevant somatic variants by WES of pure samples
  • Low-pass WGS and WES from pure cells: highly consistent & informative results
  • Reveal Loss of Heterozigosity(LOH)...
  • ...and homozygous deletions
  • Scalable workflows & benefit:from Targeted Amplicons to Omics assays
  • Conclusion
 

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