Applied BioCode AMP 2017 Workshop - "Digital MDx-3000: An Efficient, Automated Solution for Highly Multiplexed Syndromic Panel Tests"
Tuesday, March 6, 2018
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Chapters
Introduction
Company Background
Company Milestones
Barcoded Magnetic Beads (BMB)-Digital Technology
BMB Composition & Fabrication: Semiconductor Fabrication method
Application of BMB Technology Biochemistry for Nucleic Acids and Protein Detection
Multiplex Detection Method Schematic for endpoint PCR detection using BMB
Application of BMB Technology Optical Imaging & Detection
Applied BioCode Technology Multiplex Applications/ Capabilities
Strong Intellectual Property (IP) Biocompatible Barcodes
BioCode MDx 3000 – Automation System Highlights
Applied BioCode GI Panel: Scalable Workflow with MDx 3000
BioCode MDx 3000 Software/User Interface Features
BioCode MDx 3000 Software/User Interface Features
Gastrointestinal Pathogen Tests Current Practice
Gastrointestinal Pathogen Panel
BioCode GI Pathogen Panel
GI Panel Clinical Trials: 4 geographically distinct sites (1561 prospective samples)
Future Panels Respiratory Panel (Nasopharyngeal Swab)
Applied BioCode MDx 3000 Key System features
Applied BioCode, Inc. Experienced Management Team
Introduction - Dr. Anami Patel
Current Testing at Poplar Healthcare
Current Sample Processing
Challenges with Current Testing using Luminex xTAG
BioCode MDx 3000* Automated High-throughput system
BioCode MDx 3000 System*
BioCode MDx 3000: GI Test workflow
Applied BioCode MDx 3000
BioCode MDx 3000 Features
BioCode MDx 3000 Operation
BioCode MDx 3000 System: Layout
BioCode MDx 3000 System Specifications
BioCode MDx 3000 : Maintenance
BioCode MDx 3000’s GI Panel Testing: Automated High-throughput system
BioCode MDx 3000’s GI Panel
Beta-testing Data @ Poplar Healthcare
BioCode MDx 3000 GI Panel: Intra-Assay Variability
BioCode MDx 3000 GI Panel: Clinical Performance (300 samples compared to Luminex GPP)
BioCode MDx 3000 GI Panel: Clinical Performance (100 samples compared to BioFire GI)
BioCode MDx 3000 GI Panel: Reproducibility
Clinical Samples with Previous Internal Control Failures Retested on BioCode GI Panel
Summary of Beta-testing
BioCode MDx 3000 GI Panel: Training
Flexibility and Ease of Use QC Trending
BioCode MDx 3000 GI Panel: Work Flow – 94 Samples
BioCode MDx 3000 GI Panel: Work Flow – 188 Samples
Work Flow
Current Method vs. BioCode MDx 3000
Summary
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