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ATCC Molecular Signature Panels – Powerful tools for the genomics age

Wednesday, January 15, 2014
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Chapters

  • Introduction
  • Who we are
  • Outline
  • NGS leads to genomic age
  • Somatic mutations in cancer
  • The changing landscape
  • ATCC Tumor Cell Panels
  • ATCC Molecular Signature Cell Panels
  • Molecular Signature Cell Panels
  • EGFR introduction
  • EGFR cell panel characteristics
  • EGFR cell panel mRNA expression
  • EGFR Cell Panel Protein Expression
  • EGFR Cell Panel IF staining
  • EGFR panel cell growth kinetics
  • EGFR cell panel culture conditions
  • EGFR panel cell morphology
  • PI3k pathway
  • PIK3CA Mutation Cells Lines and Panel
  • Genetic alterations affect drug sensitivity
  • ERK somatic mutations
  • ERK Genetic Alteration Panel
  • Recommended control
  • Molecular signature panels to facilitate novel anti-cancer drug discovery
  • Tumor heterogeneity
  • Using authenticated cell lines as controls
  • KRAS mutation CRM cell lines and DNAs
  • Some useful cell line databases
  • Conclusion
  • Q&A
 

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