Contemporary LC-MS based lipidomics applied in the study of lung diseases
Koen Sandra
Tuesday, June 16, 2015
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Chapters
Introduction
Introduction to lipidomics
Targeted lipid analysis
Lipidomics: non-targeted/unbiased
The lipidome: an analytical challenging complexity to tackle
Tackling the lipidome by LC-MS
Human blood plasma lipid complexity revealed by LC-MS
Human skin lipid complexity revealed by LC-MS
Sputum lipidome complexity revealed by LC-MS
Accurate mass/retention time (AMRT) library
Lipidomics study of lung diseases 1
From chromatogram to potential marker
Lung sputum normalization
Lipidome differentiates healthy individuals from COPD patients
Lipidomics study of lung diseases 2
Effect of smoking cessation – endogenous compounds
Effect of smoking cessation – exogenous compounds
Comparison 6540 – 6545 Q-TOF
Ion mobility Q-TOF MS
Literature
Acknowledgement
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